I16V (p.Ile16Val) variant of HTR2C (5-hydroxytryptamine receptor 2C)
I16V (p.Ile16Val) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
I16V (p.Ile16Val) variant details
- p.Ile16Val
- gnomAD X-114731304-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.187
- REVEL 0.08
- MetaLR 0.07
- MetaSVM -1.01
- CADD 16.60
- PolyPhen-2 0.01
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available