I16S (p.Ile16Ser) variant of HTR2C (5-hydroxytryptamine receptor 2C)
I16S (p.Ile16Ser) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
I16S (p.Ile16Ser) variant details
- p.Ile16Ser
- gnomAD X-114731305-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.21
- MetaLR 0.08
- MetaSVM -1.02
- CADD 25.00
- PolyPhen-2 0.46
- SIFT 0.73
- Population evidence available
- Structural context available
- Literature evidence available