H9Y (p.His9Tyr) variant of HTR2C (5-hydroxytryptamine receptor 2C)
H9Y (p.His9Tyr) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
H9Y (p.His9Tyr) variant details
- p.His9Tyr
- ExAC rs781962054
- gnomAD rs781962054
- Missense
- Variant Prioritization Score for Impact Estimate 0.286
- REVEL 0.11
- MetaLR 0.07
- MetaSVM -1.07
- CADD 22.00
- PolyPhen-2 0.16
- SIFT 0.04
- Population evidence available
- Structural context available