H9L (p.His9Leu) variant of HTR2C (5-hydroxytryptamine receptor 2C)
H9L (p.His9Leu) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
H9L (p.His9Leu) variant details
- p.His9Leu
- gnomAD X-114726962-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.05
- MetaLR 0.06
- MetaSVM -1.07
- CADD 15.70
- PolyPhen-2 0.04
- SIFT 0.07
- Population evidence available
- Structural context available
- Literature evidence available