F11S (p.Phe11Ser) variant of HTR2C (5-hydroxytryptamine receptor 2C)
F11S (p.Phe11Ser) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
F11S (p.Phe11Ser) variant details
- p.Phe11Ser
- gnomAD X-114726968-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.21
- MetaLR 0.09
- MetaSVM -1.05
- CADD 24.50
- PolyPhen-2 0.48
- SIFT 0.26
- Population evidence available
- Structural context available
- Literature evidence available