F11L (p.Phe11Leu) variant of HTR2C (5-hydroxytryptamine receptor 2C)
F11L (p.Phe11Leu) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
F11L (p.Phe11Leu) variant details
- p.Phe11Leu
- ExAC rs782136328
- gnomAD rs782136328
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.05
- MetaLR 0.05
- MetaSVM -1.01
- CADD 9.08
- PolyPhen-2 0.00
- SIFT 0.41
- Population evidence available
- Structural context available