F11I (p.Phe11Ile) variant of HTR2C (5-hydroxytryptamine receptor 2C)
F11I (p.Phe11Ile) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
F11I (p.Phe11Ile) variant details
- p.Phe11Ile
- gnomAD X-114726967-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.263
- REVEL 0.03
- MetaLR 0.08
- MetaSVM -1.05
- CADD 11.50
- PolyPhen-2 0.06
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available