D24Y (p.Asp24Tyr) variant of HTR2C (5-hydroxytryptamine receptor 2C)
D24Y (p.Asp24Tyr) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
D24Y (p.Asp24Tyr) variant details
- p.Asp24Tyr
- gnomAD X-114731328-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.24
- MetaLR 0.12
- MetaSVM -0.95
- CADD 23.00
- PolyPhen-2 0.52
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available