D24G (p.Asp24Gly) variant of HTR2C (5-hydroxytryptamine receptor 2C)
D24G (p.Asp24Gly) in HTR2C (5-hydroxytryptamine receptor 2C) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
D24G (p.Asp24Gly) variant details
- p.Asp24Gly
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.17
- MetaLR 0.10
- MetaSVM -0.97
- CADD 18.90
- PolyPhen-2 0.31
- SIFT 0.24
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available