Y111H (p.Tyr111His) variant of HTR2A (5-hydroxytryptamine receptor 2A)
Y111H (p.Tyr111His) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
Y111H (p.Tyr111His) variant details
- p.Tyr111His
- gnomAD 13-46895576-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.599
- REVEL 0.65
- MetaLR 0.20
- MetaSVM -0.55
- CADD 29.90
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available