W76L (p.Trp76Leu) variant of HTR2A (5-hydroxytryptamine receptor 2A)
W76L (p.Trp76Leu) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
W76L (p.Trp76Leu) variant details
- p.Trp76Leu
- ExAC rs760868845
- gnomAD rs760868845
- Missense
- Variant Prioritization Score for Impact Estimate 0.529
- REVEL 0.43
- MetaLR 0.12
- MetaSVM -1.08
- CADD 28.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available