W151R (p.Trp151Arg) variant of HTR2A (5-hydroxytryptamine receptor 2A)
W151R (p.Trp151Arg) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
W151R (p.Trp151Arg) variant details
- p.Trp151Arg
- TOPMed rs1951062407
- Missense
- Variant Prioritization Score for Impact Estimate 0.649
- REVEL 0.72
- MetaLR 0.32
- MetaSVM -0.21
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available