V150L (p.Val150Leu) variant of HTR2A (5-hydroxytryptamine receptor 2A)
V150L (p.Val150Leu) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
V150L (p.Val150Leu) variant details
- p.Val150Leu
- gnomAD 13-46892555-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.154
- REVEL 0.02
- MetaLR 0.06
- MetaSVM -1.05
- CADD 15.30
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available
- Literature evidence available