V150I (p.Val150Ile) variant of HTR2A (5-hydroxytryptamine receptor 2A)
V150I (p.Val150Ile) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
V150I (p.Val150Ile) variant details
- p.Val150Ile
- gnomAD 13-46892555-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.14
- REVEL 0.02
- MetaLR 0.03
- MetaSVM -0.97
- CADD 8.79
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available