T39I (p.Thr39Ile) variant of HTR2A (5-hydroxytryptamine receptor 2A)
T39I (p.Thr39Ile) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
T39I (p.Thr39Ile) variant details
- p.Thr39Ile
- Ensembl rs1951097639
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.11
- MetaLR 0.08
- MetaSVM -1.00
- CADD 13.30
- PolyPhen-2 0.00
- SIFT 0.60
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available