T25S (p.Thr25Ser) variant of HTR2A (5-hydroxytryptamine receptor 2A)
T25S (p.Thr25Ser) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
T25S (p.Thr25Ser) variant details
- p.Thr25Ser
- 1000Genomes rs1805055
- ESP rs1805055
- ExAC rs1805055
- TOPMed rs1805055
- Missense
- Variant Prioritization Score for Impact Estimate 0.305
- REVEL 0.10
- MetaLR 0.06
- MetaSVM -1.06
- CADD 17.20
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available