T25I (p.Thr25Ile) variant of HTR2A (5-hydroxytryptamine receptor 2A)
T25I (p.Thr25Ile) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
T25I (p.Thr25Ile) variant details
- p.Thr25Ile
- cosmic curated COSV66328
- 1000Genomes rs1805055
- ESP rs1805055
- ExAC rs1805055
- Missense
- Variant Prioritization Score for Impact Estimate 0.278
- REVEL 0.02
- MetaLR 0.08
- MetaSVM -1.05
- CADD 22.30
- PolyPhen-2 0.03
- SIFT 0.26
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available