T15M (p.Thr15Met) variant of HTR2A (5-hydroxytryptamine receptor 2A)
T15M (p.Thr15Met) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
T15M (p.Thr15Met) variant details
- p.Thr15Met
- ExAC rs754812239
- gnomAD rs754812239
- Missense
- Variant Prioritization Score for Impact Estimate 0.127
- REVEL 0.07
- MetaLR 0.08
- MetaSVM -1.03
- CADD 13.70
- PolyPhen-2 0.02
- SIFT 0.01
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available