T14I (p.Thr14Ile) variant of HTR2A (5-hydroxytryptamine receptor 2A)
T14I (p.Thr14Ile) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
T14I (p.Thr14Ile) variant details
- p.Thr14Ile
- ExAC rs778929461
- TOPMed rs778929461
- gnomAD rs778929461
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.10
- MetaLR 0.07
- MetaSVM -1.07
- CADD 13.50
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available