T14A (p.Thr14Ala) variant of HTR2A (5-hydroxytryptamine receptor 2A)
T14A (p.Thr14Ala) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
T14A (p.Thr14Ala) variant details
- p.Thr14Ala
- ExAC rs747855847
- gnomAD rs747855847
- Missense
- Variant Prioritization Score for Impact Estimate 0.179
- REVEL 0.02
- MetaLR 0.09
- MetaSVM -1.04
- CADD 7.40
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available