T109P (p.Thr109Pro) variant of HTR2A (5-hydroxytryptamine receptor 2A)
T109P (p.Thr109Pro) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
T109P (p.Thr109Pro) variant details
- p.Thr109Pro
- TOPMed rs1274149032
- gnomAD rs1274149032
- Missense
- Variant Prioritization Score for Impact Estimate 0.651
- REVEL 0.77
- MetaLR 0.19
- MetaSVM -0.63
- CADD 29.60
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available