S64L (p.Ser64Leu) variant of HTR2A (5-hydroxytryptamine receptor 2A)
S64L (p.Ser64Leu) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
S64L (p.Ser64Leu) variant details
- p.Ser64Leu
- cosmic curated COSV10654
- Ensembl rs779934468
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- REVEL 0.06
- MetaLR 0.04
- MetaSVM -1.06
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.65
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available