S40T (p.Ser40Thr) variant of HTR2A (5-hydroxytryptamine receptor 2A)
S40T (p.Ser40Thr) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
S40T (p.Ser40Thr) variant details
- p.Ser40Thr
- ExAC rs778501828
- gnomAD rs778501828
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.16
- MetaLR 0.21
- MetaSVM -0.83
- CADD 24.20
- PolyPhen-2 0.90
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available