S34Y (p.Ser34Tyr) variant of HTR2A (5-hydroxytryptamine receptor 2A)
S34Y (p.Ser34Tyr) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
S34Y (p.Ser34Tyr) variant details
- p.Ser34Tyr
- gnomAD rs1175892869
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.08
- MetaLR 0.11
- MetaSVM -0.98
- CADD 23.10
- PolyPhen-2 0.19
- SIFT 0.24
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available