S29G (p.Ser29Gly) variant of HTR2A (5-hydroxytryptamine receptor 2A)
S29G (p.Ser29Gly) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
S29G (p.Ser29Gly) variant details
- p.Ser29Gly
- ExAC rs770043192
- Missense
- Variant Prioritization Score for Impact Estimate 0.137
- REVEL 0.09
- MetaLR 0.07
- MetaSVM -1.06
- CADD 11.80
- PolyPhen-2 0.00
- SIFT 0.57
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available