S17T (p.Ser17Thr) variant of HTR2A (5-hydroxytryptamine receptor 2A)
S17T (p.Ser17Thr) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
S17T (p.Ser17Thr) variant details
- p.Ser17Thr
- ExAC rs765936117
- gnomAD rs765936117
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.08
- MetaLR 0.07
- MetaSVM -0.98
- CADD 20.10
- PolyPhen-2 0.07
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available