R26K (p.Arg26Lys) variant of HTR2A (5-hydroxytryptamine receptor 2A)
R26K (p.Arg26Lys) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
R26K (p.Arg26Lys) variant details
- p.Arg26Lys
- gnomAD rs1295715779
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.08
- MetaLR 0.09
- MetaSVM -1.02
- CADD 18.30
- PolyPhen-2 0.00
- SIFT 0.63
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available