P144T (p.Pro144Thr) variant of HTR2A (5-hydroxytryptamine receptor 2A)
P144T (p.Pro144Thr) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data, published literature, and structural context.
P144T (p.Pro144Thr) variant details
- p.Pro144Thr
- gnomAD 13-46892573-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.6
- REVEL 0.56
- MetaLR 0.26
- MetaSVM -0.66
- CADD 28.10
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available
- Literature evidence available