P144Q (p.Pro144Gln) variant of HTR2A (5-hydroxytryptamine receptor 2A)
P144Q (p.Pro144Gln) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
P144Q (p.Pro144Gln) variant details
- p.Pro144Gln
- gnomAD 13-46892572-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.572
- REVEL 0.49
- MetaLR 0.27
- MetaSVM -0.52
- CADD 28.90
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available