N16S (p.Asn16Ser) variant of HTR2A (5-hydroxytryptamine receptor 2A)
N16S (p.Asn16Ser) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
N16S (p.Asn16Ser) variant details
- p.Asn16Ser
- TOPMed rs1757675998
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.11
- MetaLR 0.08
- MetaSVM -1.03
- CADD 20.80
- PolyPhen-2 0.00
- SIFT 0.55
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available