M19K (p.Met19Lys) variant of HTR2A (5-hydroxytryptamine receptor 2A)
M19K (p.Met19Lys) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
M19K (p.Met19Lys) variant details
- p.Met19Lys
- TOPMed rs1052540084
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.04
- MetaLR 0.09
- MetaSVM -1.01
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.07
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available