M121T (p.Met121Thr) variant of HTR2A (5-hydroxytryptamine receptor 2A)
M121T (p.Met121Thr) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
M121T (p.Met121Thr) variant details
- p.Met121Thr
- gnomAD rs1188200387
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.49
- MetaLR 0.18
- MetaSVM -0.77
- CADD 25.30
- PolyPhen-2 0.69
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.9e-05)
- Structural context available