L94F (p.Leu94Phe) variant of HTR2A (5-hydroxytryptamine receptor 2A)
L94F (p.Leu94Phe) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.75 / 1. The record also includes population frequency data and structural context.
L94F (p.Leu94Phe) variant details
- p.Leu94Phe
- TOPMed rs1215391625
- gnomAD rs1215391625
- Missense
- Variant Prioritization Score for Impact Estimate 0.748
- REVEL 0.74
- MetaLR 0.68
- MetaSVM 0.41
- CADD 28.50
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available