L87V (p.Leu87Val) variant of HTR2A (5-hydroxytryptamine receptor 2A)
L87V (p.Leu87Val) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
L87V (p.Leu87Val) variant details
- p.Leu87Val
- TOPMed rs1364080876
- gnomAD rs1364080876
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.06
- MetaLR 0.03
- MetaSVM -1.04
- CADD 22.10
- SIFT 0.60
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available