L71V (p.Leu71Val) variant of HTR2A (5-hydroxytryptamine receptor 2A)
L71V (p.Leu71Val) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
L71V (p.Leu71Val) variant details
- p.Leu71Val
- TOPMed rs1442771238
- gnomAD rs1442771238
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.04
- MetaLR 0.05
- MetaSVM -1.05
- CADD 18.50
- PolyPhen-2 0.00
- SIFT 0.42
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available