L21I (p.Leu21Ile) variant of HTR2A (5-hydroxytryptamine receptor 2A)
L21I (p.Leu21Ile) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
L21I (p.Leu21Ile) variant details
- p.Leu21Ile
- 1000Genomes rs185040200
- ExAC rs185040200
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.11
- MetaLR 0.06
- MetaSVM -1.07
- CADD 14.60
- SIFT 0.39
- Most common in the 1KG:CHS population (allele frequency 0.0049)
- Structural context available