L147F (p.Leu147Phe) variant of HTR2A (5-hydroxytryptamine receptor 2A)
L147F (p.Leu147Phe) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data, published literature, and structural context.
L147F (p.Leu147Phe) variant details
- p.Leu147Phe
- gnomAD 13-46892564-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.16
- MetaLR 0.12
- MetaSVM -1.02
- CADD 27.40
- PolyPhen-2 0.74
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available