L136M (p.Leu136Met) variant of HTR2A (5-hydroxytryptamine receptor 2A)
L136M (p.Leu136Met) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
L136M (p.Leu136Met) variant details
- p.Leu136Met
- gnomAD 13-46895501-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.307
- REVEL 0.14
- MetaLR 0.13
- MetaSVM -1.04
- CADD 23.60
- PolyPhen-2 0.82
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available