L116P (p.Leu116Pro) variant of HTR2A (5-hydroxytryptamine receptor 2A)
L116P (p.Leu116Pro) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data, published literature, and structural context.
L116P (p.Leu116Pro) variant details
- p.Leu116Pro
- gnomAD 13-46895560-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.812
- REVEL 0.89
- MetaLR 0.92
- MetaSVM 0.98
- CADD 26.90
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available