K146Q (p.Lys146Gln) variant of HTR2A (5-hydroxytryptamine receptor 2A)
K146Q (p.Lys146Gln) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
K146Q (p.Lys146Gln) variant details
- p.Lys146Gln
- gnomAD rs1425158265
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.18
- MetaLR 0.14
- MetaSVM -0.89
- CADD 19.30
- PolyPhen-2 0.04
- SIFT 0.61
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available