I93T (p.Ile93Thr) variant of HTR2A (5-hydroxytryptamine receptor 2A)
I93T (p.Ile93Thr) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data and structural context.
I93T (p.Ile93Thr) variant details
- p.Ile93Thr
- ExAC rs745387744
- gnomAD rs745387744
- Missense
- Variant Prioritization Score for Impact Estimate 0.52
- REVEL 0.50
- MetaLR 0.21
- MetaSVM -0.82
- CADD 28.00
- PolyPhen-2 0.92
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available