I118V (p.Ile118Val) variant of HTR2A (5-hydroxytryptamine receptor 2A)
I118V (p.Ile118Val) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
I118V (p.Ile118Val) variant details
- p.Ile118Val
- ExAC rs765850021
- gnomAD rs765850021
- Missense
- Variant Prioritization Score for Impact Estimate 0.272
- REVEL 0.09
- MetaLR 0.02
- MetaSVM -1.02
- CADD 18.30
- PolyPhen-2 0.08
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available