G35R (p.Gly35Arg) variant of HTR2A (5-hydroxytryptamine receptor 2A)
G35R (p.Gly35Arg) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
G35R (p.Gly35Arg) variant details
- p.Gly35Arg
- cosmic curated COSV10749
- 1000Genomes rs1046592807
- TOPMed rs1046592807
- gnomAD rs1046592807
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.07
- MetaLR 0.07
- MetaSVM -1.03
- CADD 9.57
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available