G138R (p.Gly138Arg) variant of HTR2A (5-hydroxytryptamine receptor 2A)
G138R (p.Gly138Arg) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
G138R (p.Gly138Arg) variant details
- p.Gly138Arg
- gnomAD rs1246174393
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.14
- MetaLR 0.13
- MetaSVM -1.05
- CADD 33.00
- PolyPhen-2 0.77
- SIFT 0.13
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available