G138E (p.Gly138Glu) variant of HTR2A (5-hydroxytryptamine receptor 2A)
G138E (p.Gly138Glu) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
G138E (p.Gly138Glu) variant details
- p.Gly138Glu
- gnomAD 13-46892590-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.357
- REVEL 0.16
- MetaLR 0.36
- MetaSVM -0.34
- CADD 23.10
- PolyPhen-2 0.03
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 1.3e-05)
- Structural context available
- Literature evidence available