F32L (p.Phe32Leu) variant of HTR2A (5-hydroxytryptamine receptor 2A)
F32L (p.Phe32Leu) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
F32L (p.Phe32Leu) variant details
- p.Phe32Leu
- TOPMed rs1414598346
- gnomAD rs1414598346
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- REVEL 0.17
- MetaLR 0.06
- MetaSVM -1.04
- CADD 19.10
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available