F112C (p.Phe112Cys) variant of HTR2A (5-hydroxytryptamine receptor 2A)
F112C (p.Phe112Cys) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data, published literature, and structural context.
F112C (p.Phe112Cys) variant details
- p.Phe112Cys
- gnomAD 13-46895572-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.824
- REVEL 0.91
- MetaLR 0.82
- MetaSVM 0.94
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available