E36K (p.Glu36Lys) variant of HTR2A (5-hydroxytryptamine receptor 2A)
E36K (p.Glu36Lys) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
E36K (p.Glu36Lys) variant details
- p.Glu36Lys
- Ensembl rs868475357
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.10
- MetaLR 0.09
- MetaSVM -1.00
- CADD 21.30
- PolyPhen-2 0.00
- SIFT 0.64
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available