E102D (p.Glu102Asp) variant of HTR2A (5-hydroxytryptamine receptor 2A)
E102D (p.Glu102Asp) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
E102D (p.Glu102Asp) variant details
- p.Glu102Asp
- TOPMed rs1453338877
- gnomAD rs1453338877
- Missense
- Variant Prioritization Score for Impact Estimate 0.358
- REVEL 0.19
- MetaLR 0.06
- MetaSVM -1.14
- CADD 25.10
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available