D23G (p.Asp23Gly) variant of HTR2A (5-hydroxytryptamine receptor 2A)
D23G (p.Asp23Gly) in HTR2A (5-hydroxytryptamine receptor 2A) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
D23G (p.Asp23Gly) variant details
- p.Asp23Gly
- ExAC rs762264146
- gnomAD rs762264146
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.06
- MetaLR 0.05
- MetaSVM -1.04
- CADD 11.30
- PolyPhen-2 0.00
- SIFT 0.46
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available